Types of Genetic Metabolic Diseases?
There are many types of genetic metabolic diseases (GMDs), which are disorders caused by genetic mutations. GMDs can cause problems with how the body uses energy, which can lead to health problems including diabetes, heart disease, and cancer. Some common types of GMDs include mitochondrial diseases, cystic fibrosis, and sickle cell anemia.
Mitochondrial diseases are a subset of GMDs caused by mutations in the mitochondrial DNA (mtDNA). These mutations can cause problems with the mitochondria – the tiny energy generators inside cells – which can lead to a variety of health problems. Mitochondrial diseases can be fatal if not treated, but there are treatments available that can help improve symptoms.
Cystic fibrosis is another type of GMD caused by mutations in the DNA of the CF gene. The CF gene helps produce the CF protein, which is important for regulating air flow and breathing. Mutations in the CF gene can cause problems with how the CF protein is produced, which can lead to thick mucus accumulation in the lungs and other organs. Cystic fibrosis is a serious condition that requires regular treatment to prevent health problems from worsening.
Types of Genetic Metabolic Diseases
